PANTS-014e2f5894b4
Human gut 419 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.80735-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-80735-length-2992-cov-11.491938_3
Retrieval
| E-value | 2.20e-10 |
| Bitscore | 27.7 |
| Identity to nearest | 0.297 |
| Nearest characterised | EC:A0ABT4UC71 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.7 |
| RMSD to IsPETase | 23.23 Å |
| Aligned fraction | 0.230 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S316/D366/H398 |
| Ser–His | 2.82 Å |
| His–Asp | 3.13 Å |
| Cleft width | 17.06 Å |
| Cleft depth | 4.41 Å |
Aromatic clamp: PHE257, PHE361, TRP285, TRP323, TYR237
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKARLLYILLACAMLFYALSLPASAVELPFSDVADSAWYYESVERVYREDWMKGTSASTFTPNGPLTRAMLAVILWRIEGCPEVGRSAVFTDTVPDDWFAEGLSWCVGSGVFAGFQDGSFRPQDSITREQLATVFYRYAGQAGREPVGDKRPVTIQSGCAWAADACAWANEHGLFTDALGALNLCAPASRGEIAYLLDQYFPSEASPSALTENSFDSMGYLLYTPANAQPDMPLIVYLHGGHGKGSDLSVLTTTDGFPQYLADGLLGEVPAYVLIPQLSEDQRGWKPASETVMRLIDKVCEENRIDRSRVSLTGHSMGGTGTWDLALLYPDAFSRIAPMSGSVDTTASTLAAFQNTPVWAFVGEDDVVVKPESSEQFVAMLEQQNPDAKITVFPETDHVGVPQKAWLEHGGELLKWLLG