PANTS-026d5eda227d
Human gut 354 aa · assembly ERZ4560700_FASTA_predicted_cds · contig ERZ4560700.3923-Hadza-MoBio-hadza-E-H-E-1-1719--NODE-3923-length-24382-cov-17.537667_15
Retrieval
| E-value | 5.90e-11 |
| Bitscore | 29.7 |
| Identity to nearest | 0.302 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 83.1 |
| RMSD to IsPETase | 20.98 Å |
| Aligned fraction | 0.208 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S250/D300/H332 |
| Ser–His | 2.96 Å |
| His–Asp | 3.12 Å |
| Cleft width | 17.89 Å |
| Cleft depth | 2.79 Å |
Aromatic clamp: PHE191, PHE295, PHE333, TRP219, TRP257, TYR171, TYR276
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKYKKRIIVSVLLVLALVLVFALHSKKKTDSKESVSITEKKEDFKKQDIESIEEEAEITIEEKSEVKDIPSEVLVKSDSAITSHPASNQSTSSQESIQEDKPSSSNQDTSSQESIQEDKPSSSNQDSSSSQHEDIPSSFKACSINTVQLGEFKYWLYTPTNPTSNMPLIIYLHGGTGRGSDLNQLTAIDGFPQYLQKGQLGNVRAYVLIPQLPSSQTGWLNAGSAVYQLIQSTVSTYQIDRQNISLTGHSLGGAGTWELACLYPQLFARIAPLSGYINVTPENISKLKNIPVKAFVGSADKIVSPSTSLEAITVLKRMNAKADITVFSGADHFSVPRLTYLDSNIDLIDWLINN