PANTS-03faca12a583
Human gut 244 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.166020-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-166020-length-1496-cov-40.042283_2
Retrieval
| E-value | 5.90e-11 |
| Bitscore | 29.6 |
| Identity to nearest | 0.275 |
| Nearest characterised | EC:A0A5S4FJI0 |
Structure
| Method | esmfold |
| Mean pLDDT | 91.7 |
| RMSD to IsPETase | 18.36 Å |
| Aligned fraction | 0.185 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S140/D190/H222 |
| Ser–His | 2.89 Å |
| His–Asp | 3.22 Å |
| Cleft width | 17.34 Å |
| Cleft depth | 4.61 Å |
Aromatic clamp: PHE223, TRP111, TRP147, TYR229, TYR64
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MELTRRGFLSLTAASAFCLLCTGCGDAAAVSPAGALTAHTGDAGLSYWLYTPQSTGTPKTLVLYLHGGSGKGSDLNAVLEAESLPRFLQEGQLAPDAYVVMPQLPANCKGWSDCTAQLMQLLAVIKAQYPIARTALTGHSMGGTGCWDLAVAYPETFCAAAPLSGSVRLTEQNLTALQSLPVWVVVGSADTIVKPDASEQFIAALKEKNPNAQLTVREGATHFDVPQAYLDSTLGLLDWLTAAR