PANTS-0d18adef6bca
Human gut 330 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.54438-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-54438-length-4281-cov-3.203378_3
Retrieval
| E-value | 2.30e-10 |
| Bitscore | 27.7 |
| Identity to nearest | 0.295 |
| Nearest characterised | EC:A0ABV5TJR7 |
Structure
| Method | esmfold |
| Mean pLDDT | 92.1 |
| RMSD to IsPETase | 22.47 Å |
| Aligned fraction | 0.223 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S136/D186/H218 |
| Ser–His | 2.95 Å |
| His–Asp | 3.04 Å |
| Cleft width | 23.02 Å |
| Cleft depth | 4.41 Å |
Aromatic clamp: PHE143, PHE181, PHE193, PHE219, PHE77, PHE95, TRP105, TYR102, TYR58
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MRKIKIFIIFALLIISSVPTAWASGCTFEPHTFYGKEKIDYYLFTPQNATENMPLIVYLHGGSGKGDNIEKLTENGFCMWVKEGKFDGTPAYILFPQLSSKYKGWSDAKNLLKELINNVTDTYAINPNRISLTGHSMGGTGTFAVASAYPGMFSCVVPMSGSIQLTDENLDAFSSLPVWAFVGSADTIVSPSFSEEFVAALKENGCDARLTVFEGADHFSVPELAYLNENLDVVGYLTSHSKSNKITDCTDGTVSITAQLPGEYSLITARRTQGGTEQIKLTHVTVAYGKNTIPISDFDIQNGDEIMLWKDLKPIAKKYTVGQATGRKGE