PANTS-0dc11824c5b8
Human gut 196 aa · assembly ERZ4560756_FASTA_predicted_cds · contig ERZ4560756.5555-Hadza-MoBio-hadza-E-H-G-1-1731--NODE-5555-length-15734-cov-12.908092_15
Retrieval
| E-value | 4.30e-09 |
| Bitscore | 23.5 |
| Identity to nearest | 0.279 |
| Nearest characterised | HGMP02 |
Structure
| Method | esmfold |
| Mean pLDDT | 85.9 |
| RMSD to IsPETase | 12.85 Å |
| Aligned fraction | 0.189 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S83/D140/H173 |
| Ser–His | 3.1 Å |
| His–Asp | 2.94 Å |
| Cleft width | 19.12 Å |
| Cleft depth | 2.73 Å |
Aromatic clamp: PHE175, PHE19, PHE21, PHE37, TRP24, TRP36, TYR107, TYR48
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
ADMTTLKSLAMSGVACYTFDFYGWTDRSTGPQGARWFHDVPRGVDDSYEKKVLQQVEDLNAVIEAAKNWDFVDTNRLYLVGSSMGGATVATAAVTHSDDIRGIVLEYPAINLNPDAMVSGAPLDVNGYTGPVLILQGTKDVIVPMEISQNLTAHYNTLRDDHAELIIYEGQPHVFTGKYKVLAAKEIYRFLEETTS