PANTS-1a7940ecbc25
Human gut 223 aa · assembly ERZ4239636_FASTA_predicted_cds · contig ERZ4239636.37134-NODE-37134-length-671-cov-2.508117_1
Retrieval
| E-value | 4.40e-12 |
| Bitscore | 33.3 |
| Identity to nearest | 0.284 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.3 |
| RMSD to IsPETase | 11.43 Å |
| Aligned fraction | 0.174 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S124/D172/H204 |
| Ser–His | 2.99 Å |
| His–Asp | 3.04 Å |
| Cleft width | 21.49 Å |
| Cleft depth | 3.27 Å |
Aromatic clamp: PHE167, PHE199, PHE211, PHE27, TRP207, TRP73, TYR131, TYR72, TYR75
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
SKGDSLPYRMIHPESVKPGEKYPLVLFLHGAGERGNDNEKQLTHGGQMFLNPVNQEKYPAFVLIPQCPTDGYWAYTGRPKSLIPTEMPVGQEISPILQTLKQLLDSYLVMPEVDTQRVYIIGLSMGAMGTYDLVVRYPEIFAAAVPICGTVNPSRLSVAKDVKFRIFHGDADDVVPVKGSREAYKALKAAGADVEYIEFPGCNHGSWNPAFNYPGFMDWLFKQ