PANTS-227076ee89fd
Human gut 262 aa · assembly ERZ24772302_FASTA_predicted_cds · contig ERZ24772302.17492-NODE-17492-length-3827-cov-9.151644_2
Retrieval
| E-value | 1.20e-07 |
| Bitscore | 18.8 |
| Identity to nearest | 0.272 |
| Nearest characterised | EC:A0ABQ4H167 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.5 |
| RMSD to IsPETase | 13.32 Å |
| Aligned fraction | 0.208 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S160/D209/H241 |
| Ser–His | 2.96 Å |
| His–Asp | 3.1 Å |
| Cleft width | 20.47 Å |
| Cleft depth | 3.44 Å |
Aromatic clamp: PHE123, PHE167, PHE216, PHE248, PHE62, TRP108, TRP244, TYR111, TYR204, TYR236
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKTRTNWLILLIFTFLSTSLYAGDKTSFLKKQFTAQNGYKLNYRILYPLNYSPDKQYPIILFLHGGGEKGSDNESQLLHGGDMFASYENQSNYPAIIIAPQCPEGETWAPYLHPSQNNGKREFPYSAPATKAMKAVKEMLDCYIDKGIVDTKRIYITGLSMGGIGTFDVVCRYPNFFAAASPICGGINLKRLENFKGKTGFSIYHGAADDVVDPQFSRDAYATLQKIHADVRYKEYPGVKHNSWDNAFAEPDYLKWMFQHSL