PANTS-2f33d772d13d
Human gut 287 aa · assembly ERZ24772406_FASTA_predicted_cds · contig ERZ24772406.16025-NODE-16025-length-2301-cov-6.314782_1
Retrieval
| E-value | 7.20e-15 |
| Bitscore | 42.5 |
| Identity to nearest | 0.259 |
| Nearest characterised | EC:A0A852TYE9 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.8 |
| RMSD to IsPETase | 10.78 Å |
| Aligned fraction | 0.204 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S127/D223/H255 |
| Ser–His | 3.16 Å |
| His–Asp | 3.17 Å |
| Cleft width | 22.57 Å |
| Cleft depth | 3.25 Å |
Aromatic clamp: PHE171, PHE228, PHE260, PHE261, TRP162, TRP52, TRP58, TYR131, TYR163, TYR173, TYR85, TYR93
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MYKRQEKPQYVAITGITYAQVDSWYGHCRRDLKLDLIYPEDFSGKTYPCVVWICGGAWLRMDRSAHFAYLSKLAQSGFVVASVEYRTSNEGEYPMQIQDVKAAIRYLRAHADRYRIDAEYFGVTGESAGGYLTCMAALDEDVSLDVGDYLEQSSRVQAACPWYPPTDTSKFQYQEAEQCAASPESLLLGFNVMKNPEKGYENSPVSKVTKEAPPFLIIHGTNDRTVPFSQSESLYEILEKNGCDVTFLVLEGADHADLQFFQDEVWERMISFFKEKLTRICQEDIKS