PANTS-3a8ed4240aea
Human gut 198 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.31133-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-31133-length-6995-cov-2.662186_2
Retrieval
| E-value | 1.00e-07 |
| Bitscore | 19.0 |
| Identity to nearest | 0.259 |
| Nearest characterised | EC:A0ABT4UC71 |
Structure
| Method | esmfold |
| Mean pLDDT | 72.0 |
| RMSD to IsPETase | 12.37 Å |
| Aligned fraction | 0.181 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S99/D146/H178 |
| Ser–His | 2.69 Å |
| His–Asp | 3.03 Å |
| Cleft width | 22.36 Å |
| Cleft depth | 4.3 Å |
Aromatic clamp: PHE141, PHE18, PHE74, TRP106, TRP181, TRP44, TYR101, TYR103, TYR183, TYR185
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MEKERGIIPKTVWLPDVFGNSYGMPQILAKSGIKYFVTHKPCVWNDTNQIPHHTFWWQGPDGLRVFAALSASHFVGTCEPDHIMLNWGRYTDKAKIGESMYCYGTWHTAMARPDLFAAIAPICGGGMAWNAHVLKMPAWVFHGAADETVSVNQSDEMVNAMRANGTDVKYTRMDGVGHGVWDYAYTDEMVKWLLSHQL