PANTS-4427a6e80bbc
Human gut 196 aa · assembly ERZ4560700_FASTA_predicted_cds · contig ERZ4560700.53328-Hadza-MoBio-hadza-E-H-E-1-1719--NODE-53328-length-3013-cov-4.744550_3
Retrieval
| E-value | 3.60e-08 |
| Bitscore | 20.5 |
| Identity to nearest | 0.221 |
| Nearest characterised | EC:A0ABW1NJ96 |
Structure
| Method | esmfold |
| Mean pLDDT | 92.5 |
| RMSD to IsPETase | 12.83 Å |
| Aligned fraction | 0.166 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S111/D158/H190 |
| Ser–His | 3.0 Å |
| His–Asp | 2.89 Å |
| Cleft width | 25.64 Å |
| Cleft depth | 4.12 Å |
Aromatic clamp: PHE153, PHE185, PHE35, TRP118, TRP193, TRP80, TYR115, TYR167, TYR50, TYR78
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MEEKIYKHPYFGEIYYLLDIPEKYKNTSGAPLLVFLHGAGERGKDHELLYRQGPPRYIREGIKTVDAITLCPQCPTEYIWNDIVIFLKDLIDSIIKEYQIDRTRVSLTGISMGGYGTWEMAMCYPEMFRKIAPVCGGGTPWRAWQIQAKIRAFHGDLDDVVPPESSYQMVDAALNAGKDASLTIFHHVNHGSWDPA