PANTS-4fb566497b51
Human gut 302 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.193213-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-193213-length-1285-cov-4.379139_1
Retrieval
| E-value | 1.90e-11 |
| Bitscore | 31.2 |
| Identity to nearest | 0.378 |
| Nearest characterised | EC:A0ABT9QDD4 |
Structure
| Method | esmfold |
| Mean pLDDT | 89.8 |
| RMSD to IsPETase | 19.00 Å |
| Aligned fraction | 0.230 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S199/D249/H281 |
| Ser–His | 2.89 Å |
| His–Asp | 3.15 Å |
| Cleft width | 17.19 Å |
| Cleft depth | 4.51 Å |
Aromatic clamp: PHE140, PHE244, PHE282, TRP168, TRP206, TYR120, TYR289
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MRKFQILLLALLIVLSGCSGRSGPSPSGTETVPPVSETEVPQTESTAQTQLTEPETTAPETTAPSATFPEPEPTEATQPSVPEPATGLQQVTLTLSHGRTADCWLYVPEAPGANPGLIVYLHGGSGKGDDLNLITEAGGFPKYLQSGQLGALSSYVLIPQLPQSLKGWSDMDNGLMDMIRTVVRTYGIDTANISLTGHSMGGTGVWSIAAAHPGFFARIAPLSGSIRNTPENVQALKDTPVYAFVGTEDTIVKPESSIAFVDALTAAGGTAQIAEIEGADHFAVPECAYLGDYGLVEWLEGM