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PETase ANnotation and Triage System

Nature's solution to a human-made problem, and structural learnings from Nature

PANTS-50c7618c98d1

Marine plastisphere 604 aa · assembly ERZ21854033_FASTA_predicted_cds · contig ERZ21854033.158-NODE-158-length-16038-cov-5.595195_13

Retrieval

E-value6.90e-13
Bitscore36.0
Identity to nearest0.316
Nearest characterisedEC:A0A919RR95

Structure

Methoddeferred
Mean pLDDT-
RMSD to IsPETase- Å
Aligned fraction-

Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.

No structure was predicted: length > 450 aa: probable fusion, multi-domain protein or misassembly. Fold time is quadratic in length and the cleft measurement assumes a single active site in one domain.

Sequence

MSLSQAFGTLRAARRVVSLGVGLVALAAAPGLAAERVVVKVGPLSQSIELSDLETFARTGEVPEGLRLYQRFLSPSLQQTLQQQLDLDPRMSDHIIEDVLRSANGELLLSTLSQVAPNMTMPQLQAAIRLAASQADGLSVLSVLRAVPQETLEVDISAAIALMTQFNFSTIENRSLSGLLAQELLVDNPAPLPSDIEPSVRGEEAVYQRSLTFRDIDRQRVIPVEIYWTSETRGPLVVLSHGFGADRYFLDYIAQHLASNGLTVASVEHPGSNLQALVNLPVDPEIVDTPSRLLPASEFLDRPRDVTFVLDRLERLTARTSIYSERFNTQDVTVIGHSLGGYTGLALAGAKLDLRSLQGFCENIQPLGVSPADWLQCAAVDLEEQQADLSDDRITQVMAMNTLTGKLFGDAGLSEITVPTLLLTGTQDSVTPTLDQQLSAFTQLSGEKYLLAVIGGTHLSVGDPGNVNPALTELPFMAELRVDETTQLRQLLRGVAFSFVQQRTGEAADYQPFLSSAYVQSFSTETLPLRLVEVLPSSVRSWLEFTDRISANQNSRKFSNRLMALGYLNALSQRSYLQAALAVHLQASQIVTVLRSPLPFIAGW