PANTS-59dbee9d8ba1
Human gut 414 aa · assembly ERZ4560321_FASTA_predicted_cds · contig ERZ4560321.86628-Hadza-MoBio-hadza-E-H-G-21-1740--NODE-86628-length-1672-cov-1.791223_1
Retrieval
| E-value | 6.70e-12 |
| Bitscore | 32.8 |
| Identity to nearest | 0.250 |
| Nearest characterised | EC:A0ABW1CGM7 |
Structure
| Method | esmfold |
| Mean pLDDT | 91.1 |
| RMSD to IsPETase | 22.27 Å |
| Aligned fraction | 0.226 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S311/D361/H393 |
| Ser–His | 2.83 Å |
| His–Asp | 3.1 Å |
| Cleft width | 16.12 Å |
| Cleft depth | 4.42 Å |
Aromatic clamp: PHE252, PHE356, TRP280, TRP318, TRP401, TYR232
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKRILNRIPAMLLAAILLAAPACAAQTSYTDVPENVWYEEAILTVTERGWMDGTGNGEFSPNDGLTRAMLATILWRMEDCPAAAVTANFTDIVRGSWYDGGVSWCVEEGLFQGFPDGSFRPNDAVTREQLAVVFYRYADAKPTAAAAKVSVKNGCSWALDACAWANAEGLFTDALGTLDLCAPANRAEIAYWLAHFDSGTSASSLTEGSFEGLGYLLYTPENAEKNMSLLVYLHGSHGKGSDLSVLTTTDGFPQYLADGLFGEVPAYVLIPQLPANEKGWLSSADTVMALIDTICKEKTIDRSRIALTGHSMGGTGTWDLALAYPDIFSRIAPMSGSIKTTSDTLKTLETMPIWAFVGEDDVVVKPESTEAFIESVSEQNSDARVTVFEATDHVGVLQKAWLENGKALLNWLLQ