PANTS-65b45a1d7c7d
Human gut 211 aa · assembly ERZ4560700_FASTA_predicted_cds · contig ERZ4560700.201994-Hadza-MoBio-hadza-E-H-E-1-1719--NODE-201994-length-885-cov-1.967822_1
Retrieval
| E-value | 2.20e-12 |
| Bitscore | 34.3 |
| Identity to nearest | 0.342 |
| Nearest characterised | EC:A0ABR9HP34 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.9 |
| RMSD to IsPETase | 11.01 Å |
| Aligned fraction | 0.128 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S112/D159/H191 |
| Ser–His | 2.96 Å |
| His–Asp | 3.07 Å |
| Cleft width | 19.81 Å |
| Cleft depth | 4.38 Å |
Aromatic clamp: PHE37, PHE80, TRP119, TRP194, TRP81, TYR116, TYR154, TYR196, TYR198
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MQRERNIIINEECCTEFKYLLYKPNKDYKKKLPLIVFLHGAGERGNDLSLLKVHSIPNMFEGNVEYPCIVVSPQCKADSFWTAQIPQLKVFIDKIAEKYQIDENCIHLTGVSMGGYGTWDLAMAYPDMFASIVPICGGGMAWNAGVLKMPIRIYHGEADTVVNVRESIEMYESLKKTNDNVTLDIFPGVDHNAWDYAYNDELILWMLKQKK