PANTS-6eb128fdb77f
Human gut 281 aa · assembly ERZ4560756_FASTA_predicted_cds · contig ERZ4560756.1158-Hadza-MoBio-hadza-E-H-G-1-1731--NODE-1158-length-48060-cov-56.050080_32
Retrieval
| E-value | 1.30e-09 |
| Bitscore | 25.2 |
| Identity to nearest | 0.233 |
| Nearest characterised | HGMP04 |
Structure
| Method | esmfold |
| Mean pLDDT | 85.4 |
| RMSD to IsPETase | 15.04 Å |
| Aligned fraction | 0.215 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S168/D225/H258 |
| Ser–His | 3.1 Å |
| His–Asp | 2.92 Å |
| Cleft width | 21.54 Å |
| Cleft depth | 2.39 Å |
Aromatic clamp: PHE104, PHE106, PHE122, PHE220, PHE260, TRP109, TRP121, TYR133, TYR192, TYR76, TYR84
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKKWMKAVLIGAGAFAVIAGIAAIVCVGHYVGFPEPAGEEKTGYRTEKLCVEYDGISLYGKALIPDGDGPFPTVVYAHGAESDYKADMTTLKSLAMSGVACYTFDFYGWTDRSTGPQGVHWFHDVPRGVDDSYEKKVLQQVEDLNAVIEAAKGWGFVDTSRLYLVGSSMGGATVATAAVTHSDDIRAIVLEYPAINLNPDAMVSGAPLDVNGYTGPVLIFQGTKDVIVPMEMSQNLATHYNTLRDDHAELVIYEGQPHVFTGKYKVPAAKEIYRFLEETAS