PANTS-77ec97640668
Human gut 258 aa · assembly ERZ24812776_FASTA_predicted_cds · contig ERZ24812776.8160-NODE-8160-length-2636-cov-7.492832_2
Retrieval
| E-value | 6.30e-12 |
| Bitscore | 32.8 |
| Identity to nearest | 0.293 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.7 |
| RMSD to IsPETase | 9.79 Å |
| Aligned fraction | 0.189 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S155/D203/H235 |
| Ser–His | 2.98 Å |
| His–Asp | 3.07 Å |
| Cleft width | 20.95 Å |
| Cleft depth | 3.31 Å |
Aromatic clamp: PHE113, PHE198, PHE230, PHE242, PHE58, TRP104, TRP238, TYR103, TYR106, TYR162
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MMKQWTTLFVFLFLSLSLSAQQGYGRDIFVSSKGDSLPYRMIHPESVKPGEKYPLVLFLHGAGERGNDNEKQLTHGGQMFLNPVNQEKYPAFVLIPQCPTDGYWAYTERPKSFIPAEMPVGQEISPILQILKQLLDSYLVMPEVDTQRVYIIGLSMGAMGTYDLVIRYPEIFAAAIPICGIVSPSRLSAAKDVKFRIFHGDADDVVPVKGSREAYKALKAAGADVEYIEFPGCNHGSWNPAFNYPGFMDWLFKQKKKR