PANTS-79e49dd125cd
Human gut 213 aa · assembly ERZ4561292_FASTA_predicted_cds · contig ERZ4561292.379-Hadza-MoBio-hadza-A-D-D-16-1621--NODE-379-length-141384-cov-14.638107_33
Retrieval
| E-value | 1.30e-07 |
| Bitscore | 18.7 |
| Identity to nearest | 0.288 |
| Nearest characterised | EC:A0A7W3N2I8 |
Structure
| Method | esmfold |
| Mean pLDDT | 89.2 |
| RMSD to IsPETase | 12.85 Å |
| Aligned fraction | 0.151 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S109/D160/H193 |
| Ser–His | 2.97 Å |
| His–Asp | 2.94 Å |
| Cleft width | 19.75 Å |
| Cleft depth | 4.25 Å |
Aromatic clamp: PHE113, PHE194, PHE200, PHE35, PHE77, TRP116, TRP78, TYR155, TYR52
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MLKKYYKLNMSDYSNMNYIVYSPETKQNNFPLLLFLHGIGERGKKIEDIEKYALPKYMNRFDIPYIVVAPQCDNNNFWDYHLRDVEKILEKVYKEYKYDKNRVCILGSSMGAFGAWNYIMSRPNLFKGIVSVSGGIMLPIKQTLLPLKEKAILIYHGNIDDVIDVNESIKAYNKLKSIDSKNIELKIIENDNHFLTSHAFKDKYLYEWLERNI