Marc C. Deller, D.Phil.
marcdeller.com eloratherapeutics.com marc@marcdeller.com GitHub DOI 10.5281/zenodo.21807353 
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PETase ANnotation and Triage System

Nature's solution to a human-made problem, and structural learnings from Nature

PANTS-9f6ec163c256

Landfill 152 aa · assembly ERZ782921_FASTA_CDS_annotated · contig ERZ782921.251261-NODE-251261-length-612-cov-1.050269_1

Retrieval

E-value3.20e-15
Bitscore43.6
Identity to nearest0.436
Nearest characterisedPLC:A0A1H2ERI7

Structure

Methodesmfold
Mean pLDDT91.7
RMSD to IsPETase5.31 Å
Aligned fraction0.192

Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.

Active site

TriadS28/D71/H101
Ser–His3.22 Å
His–Asp3.33 Å
Cleft widthNone Å
Cleft depth6.77 Å

Aromatic clamp: PHE104

Structure, superposed on IsPETase

Catalytic triad drawn as ball-and-stick from the measured residues.

Sequence

YLMQQHQDPASPFYGMLDTAKVGTTGHSQGGGGAINAATDPRVTCSAPLAPSPGDIRNVRGPIFLVAGADDTLVSPSLVRSTSFNRATAPTFFGIAKGMDHMSFTGNIGLARGYVTAWFMYHLQNDIYAGEAFIGRCEICNDTNWDVSQKNF