PANTS-a306063fcbaf
Human gut 255 aa · assembly ERZ24772302_FASTA_predicted_cds · contig ERZ24772302.672-NODE-672-length-42953-cov-13.365681_21
Retrieval
| E-value | 7.80e-12 |
| Bitscore | 32.5 |
| Identity to nearest | 0.333 |
| Nearest characterised | EC:A0A5N6AZJ9 |
Structure
| Method | esmfold |
| Mean pLDDT | 92.9 |
| RMSD to IsPETase | 11.04 Å |
| Aligned fraction | 0.174 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S154/D202/H234 |
| Ser–His | 2.93 Å |
| His–Asp | 3.14 Å |
| Cleft width | 20.7 Å |
| Cleft depth | 3.53 Å |
Aromatic clamp: PHE112, PHE161, PHE197, PHE229, PHE241, PHE57, TRP103, TRP237, TYR102, TYR105
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKRLISAICVLFFLLPLSAQETYQKETFISSRGDTLQYRLLQPENMKKSEKYPLVLFLHGAGERGNDNERQLTHGGQMFLNPVNREKYPAFVLAPQCPETGYWAYSARPESFLPNEMPLNEPITPIFQTVKDLLDTYLAMPQVDKSRIYIIGLSMGGMGTFDMAVRFPEIFAAAVPICGTVNVARLKAVKSVKFRIFHGDADNVVTPEGSRAAYRTLKKEGADVEYIEFPGCNHGSWNPAFNYPDFMSWLFSQKK