PANTS-a6bb2d5e105e
Human gut 274 aa · assembly ERZ4239610_FASTA_predicted_cds · contig ERZ4239610.1483-NODE-1483-length-7959-cov-4.312627_9
Retrieval
| E-value | 9.00e-12 |
| Bitscore | 32.3 |
| Identity to nearest | 0.315 |
| Nearest characterised | EC:A0A2P4UDP6 |
Structure
| Method | esmfold |
| Mean pLDDT | 89.4 |
| RMSD to IsPETase | 17.63 Å |
| Aligned fraction | 0.219 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S157/D205/H237 |
| Ser–His | 2.96 Å |
| His–Asp | 2.92 Å |
| Cleft width | 21.31 Å |
| Cleft depth | 3.78 Å |
Aromatic clamp: PHE101, PHE117, PHE200, PHE242, PHE244, PHE64, TRP108, TRP240, TRP68, TYR164
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MNRIVTILLLIFAALPLSVAAQSRDLNQAYKKEVFTDGRHKKMPYRLLSPKIRADHSQYPLVVFLHGWGERGDDNEKQLTNGASLFTNPANEDAYPAFVLFPQTRKTWTGNIDPRSFQHGAPEPKETQTEKTLMELINKVVAENPIDRSRIYLVGLSMGGIATYDLVCRYPDVFAAAVPICGAVNPDRLKNAKGVNFLIFHGDQDEEVPTVASREAFKTLDAIGATVKYVEFAGVGHECWSFAFNSPTFLSWLFQQEKTPAHSESIAAIPSHEE