PANTS-b25c2f02cdb0
Human gut 413 aa · assembly ERZ4561272_FASTA_predicted_cds · contig ERZ4561272.116995-Hadza-MoBio-hadza-A-D-F-2-1628--NODE-116995-length-1650-cov-13.185633_2
Retrieval
| E-value | 1.10e-10 |
| Bitscore | 28.7 |
| Identity to nearest | 0.259 |
| Nearest characterised | EC:A0A3D9SPQ3 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.6 |
| RMSD to IsPETase | 21.38 Å |
| Aligned fraction | 0.223 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S310/D360/H392 |
| Ser–His | 2.91 Å |
| His–Asp | 3.06 Å |
| Cleft width | 16.47 Å |
| Cleft depth | 4.43 Å |
Aromatic clamp: PHE251, PHE355, TRP279, TRP317, TRP400, TYR231
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKIKFSHLLLASSLLISSLNVSAAAASFTDVEPSAWYYDAVENVTENGWLNGTGGSCFTPNGDLTRAMLATILWRIEGSPAPNGSADFIDTDSASWYADGLAWSVENGLFNGYPDGSFRPANAITREQLAAVFYRTAEDKTDIGVGAIRTKNGCSWASEACAWANAHGLFPYALGTLDLCAPASRAEIAYWLNAYDPQETQSTLTEGQYSSMGYLLYTPANAQADMPLIVYLHGGHGKGSDLSILTTTDGFPQYLADGTLGEIPAYVLIPQLPADQNGWKAADDTVMSLIDKICTENKIDRSRISLTGHSMGGTGTWDIALLHPEVFSRIAPMSGSIQTTAETLAALRDMPIRTFVGDADRVVKPESAEQFIAALQEQNANAKLTVFADTDHVGVLRTAWLEDGAALIDWLIQ