PANTS-b976dd3ca628
Human gut 291 aa · assembly ERZ4560928_FASTA_predicted_cds · contig ERZ4560928.5669-Hadza-MoBio-C-REDO-E-3-1554--NODE-5669-length-7376-cov-2.880258_8
Retrieval
| E-value | 3.50e-15 |
| Bitscore | 43.5 |
| Identity to nearest | 0.314 |
| Nearest characterised | EC:A0ABW2Y2H3 |
Structure
| Method | esmfold |
| Mean pLDDT | 91.1 |
| RMSD to IsPETase | 11.95 Å |
| Aligned fraction | 0.189 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S131/D227/H259 |
| Ser–His | 3.16 Å |
| His–Asp | 3.26 Å |
| Cleft width | 22.63 Å |
| Cleft depth | 3.18 Å |
Aromatic clamp: PHE175, PHE232, PHE264, PHE265, TRP166, TRP56, TRP62, TYR135, TYR167, TYR177, TYR89, TYR97
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKEVLKINVEKPQYVTITGITYAQVDSWYGHCRRDLKLDLIYPEDFSGKTYPCVVWICGGAWLRMDRSAHLAYLSKLAQSGFVVASVEYRTSNEGEYPMQIQDVKAAIRYLRAHADRYRIDAEYIGVTGESAGGYLTCMAALDEAVSLDVGDYLEQSSKVQAACPWYPPTDTSKFPYQNAEQCAASPESLLLGFNVMRNPKKGYENSPVSKVTKDAPPFLIIHGMNDHTVPFSQSESLYETLEANGCDVTLLALEGADHADLQFFQDKIWERMISFFKEKLTRICQENIKS