Marc C. Deller, D.Phil.
marcdeller.com eloratherapeutics.com marc@marcdeller.com GitHub DOI 10.5281/zenodo.21807353 
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PETase ANnotation and Triage System

Nature's solution to a human-made problem, and structural learnings from Nature

PANTS-bebd392634fe

Marine plastisphere 646 aa · assembly ERZ21854028_FASTA_predicted_cds · contig ERZ21854028.827-NODE-827-length-12374-cov-5.902995_8

Retrieval

E-value6.10e-10
Bitscore26.3
Identity to nearest0.298
Nearest characterisedEC:A0ABV3GLG2

Structure

Methoddeferred
Mean pLDDT-
RMSD to IsPETase- Å
Aligned fraction-

Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.

No structure was predicted: length > 450 aa: probable fusion, multi-domain protein or misassembly. Fold time is quadratic in length and the cleft measurement assumes a single active site in one domain.

Sequence

MRVRQFLVVCFGIMGLSATAVAQPTPVPVEVWADRNQVLELDMSPNASRMAMLMRRERGGDPELMIFETGDIRGTLEAIQPEGLVPQSLRWANDDLLIVNFFFQTEDRGRPVVLSRSASYDVTSGEWTSMVRTTSTRDIRTSGSSLMGELGIGQVINILADDPDHVLISHNEEAGKAPNYYRVNLNNGRRNLVLRGNDRFGGYIWDRQGNARGATEYDAAANAIVSMARVSPDDDWKEVGRLRADSRDRFSLIGFYDSERPYIATVVADEPGGNNTAIFEVDIRNGDKEMIFGTTQYDALGVILSPRLADGTKVVGYTYSDEGGYQNYFTDPDYAALYEGLSQAFPGRNVDIERVSEDGSTTLVFTQGPQDPGTWYLLRGGQVAPVISSSTEITAEALSPVEVITYDARDGLEVSGYVTIPANMEGPFPTIAMPHGGPWVRDTYGYDEWAQMLANQGYAVFQPNYRGSTNLGKAFWLAGDNRWGFEMQDDIDDGMMALVDRGIADPERLAIFGWSYGGYAAFTAATRDNGMYNCIVSGAGVSDLTRIRGGLSGSRFLREYQKPTIGGVSPVDLADNVTKPMLIVHGDYDSTVPVEHSRRFVAGLERINADFTYIEIEDMGHSPFFYQQNMQWFPELLEFFDSKCGF