PANTS-c72d05ef5fe6
Human gut 428 aa · assembly ERZ24772406_FASTA_predicted_cds · contig ERZ24772406.30551-NODE-30553-length-1364-cov-6.245225_2
Retrieval
| E-value | 1.90e-11 |
| Bitscore | 31.3 |
| Identity to nearest | 0.311 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 88.7 |
| RMSD to IsPETase | 21.92 Å |
| Aligned fraction | 0.238 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S330/D380/H412 |
| Ser–His | 2.86 Å |
| His–Asp | 3.06 Å |
| Cleft width | 18.71 Å |
| Cleft depth | 4.32 Å |
Aromatic clamp: PHE271, PHE375, PHE413, TRP299, TRP337, TYR251, TYR418
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MRKTKWMAAVLSVCLILVMLPTVAFAEGHAKSTGNAEHDNPFGDIHEGDYYYDAVLWAVEQGITSGTSATTFSPDTSCTRSQMVTFLWRSAGSPHAQYTVSPFEDVSSDTYYYEAVIWAAEQGITSGTSSTTFSPDTTITRAQAITFIFRAMEAPAPAQSASFSDVPADAYYASAVSWAAEQGVTGGTSADTFSPDSDCTRGQIVTFIFRSEKNNTPSTFEANSVSNEFGSFRYWLYTPSNPTEQMPLIVYLHGGSGKGDNLSLITSEDGFPKYLQSGELGDVRAYVLIPQLPSTQKGWADVSQPLYNLIQAIVTEFHIDTGNISLTGHSMGGTGTWNLAAEYPTLFARIAPLSGSARLNADAIKKLDTLPVWAFVGSADTIVPPDSSEQIVKELEETGGTAQITIFNGADHFSCLLYTSPSPRDYAA