PANTS-c7c045f569ed
Human gut 255 aa · assembly ERZ24772302_FASTA_predicted_cds · contig ERZ24772302.1177-NODE-1177-length-31386-cov-30.767802_3
Retrieval
| E-value | 1.20e-11 |
| Bitscore | 32.0 |
| Identity to nearest | 0.293 |
| Nearest characterised | EC:A0ABQ2QK59 |
Structure
| Method | esmfold |
| Mean pLDDT | 90.7 |
| RMSD to IsPETase | 10.97 Å |
| Aligned fraction | 0.189 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S154/D202/H234 |
| Ser–His | 2.94 Å |
| His–Asp | 2.98 Å |
| Cleft width | 22.27 Å |
| Cleft depth | 3.31 Å |
Aromatic clamp: PHE113, PHE197, PHE229, PHE241, PHE57, TRP103, TRP237, TYR102, TYR105, TYR161
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKQWSILLVFLSLSLSLSAQQGYEKDVFVSSTGDSLPYRMIRPEPMKAGKKYPLVLFLHGAGERGNDNERQLTHGGQMFLNPVNREKYPAFVLVPQCPAGSYWAYTERPKSLFPADMPAGQEMSSLIRTLKQLLDTYLVMPEVDKKRIYIVGLSMGAMGTYDLVVRYPEIFAAAVPICGSVNPDRLPAAKEVKFRIFHGDADDVVTVEGSREAYKALKAAGAKVEYIEFPGCNHGSWNPAFNYPGFMEWLFKQKK