PANTS-d5ffa53ac4f9
Human gut 184 aa · assembly ERZ4560895_FASTA_predicted_cds · contig ERZ4560895.91465-Hadza-MoBio-hadza-A-D-J-9-1548--NODE-91465-length-552-cov-1.665263_1
Retrieval
| E-value | 7.90e-12 |
| Bitscore | 32.5 |
| Identity to nearest | 0.327 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 93.9 |
| RMSD to IsPETase | 10.61 Å |
| Aligned fraction | 0.155 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S95/D145/H177 |
| Ser–His | 2.95 Å |
| His–Asp | 3.15 Å |
| Cleft width | 17.7 Å |
| Cleft depth | 4.41 Å |
Aromatic clamp: PHE140, PHE178, PHE36, TRP102, TRP64, TYR16
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
LYTPTDPQQNMPLIVYLHGGSGKGDDLNLITAVDGFPSYLQSGSFGNLRAYVLIPQLPAEQKGWAEVSDQLYELIQNLLETRGIDRGNISLTGHSMGGTGTWSMGAAYPSLFARIAPLSGSVRSPESTAAKLSDTPVWAFVGSEDTIVPPESSEQTIGWLMELSDQAKITVLEGADHFSVPSLA