PANTS-ddcbf1b00e2d
Human gut 258 aa · assembly ERZ24772229_FASTA_predicted_cds · contig ERZ24772229.632-NODE-632-length-29972-cov-21.628071_4
Retrieval
| E-value | 6.20e-12 |
| Bitscore | 32.9 |
| Identity to nearest | 0.284 |
| Nearest characterised | EC:A0A8J3U475 |
Structure
| Method | esmfold |
| Mean pLDDT | 89.4 |
| RMSD to IsPETase | 9.87 Å |
| Aligned fraction | 0.196 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S155/D203/H235 |
| Ser–His | 2.94 Å |
| His–Asp | 3.04 Å |
| Cleft width | 21.59 Å |
| Cleft depth | 3.25 Å |
Aromatic clamp: PHE198, PHE230, PHE242, PHE58, TRP104, TRP238, TYR103, TYR106, TYR162
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MMKQWITLFVFLFLSLSLSAQQGYGRDIFVSSKGDSLPYRMIHPESVKPGEKYPLVLFLHGAGERGNDNEKQLTHGGQMFLNPVNQEKYPAFVLIPQCPTDGYWAYTGRPKSLIPTEMPVGQEISPILQTLKQLLDSYLVMPEVDTQRVYIIGLSMGAMGTYDLVVRYPEIFAAAVPICGTVNPSRLSVAKDVKFRIFHGDADDVVPVKGSREAYKALKAAGADVEYIEFPGCNHGSWNPAFNYPGFMDWLFKQKKKR