PANTS-e03b1a21a631
Human gut 286 aa · assembly ERZ4560756_FASTA_predicted_cds · contig ERZ4560756.21312-Hadza-MoBio-hadza-E-H-G-1-1731--NODE-21312-length-5300-cov-52.319740_4
Retrieval
| E-value | 1.70e-10 |
| Bitscore | 28.2 |
| Identity to nearest | 0.303 |
| Nearest characterised | EC:A0ABW1CGM7 |
Structure
| Method | esmfold |
| Mean pLDDT | 83.3 |
| RMSD to IsPETase | 15.49 Å |
| Aligned fraction | 0.185 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S170/D220/H252 |
| Ser–His | 2.96 Å |
| His–Asp | 3.13 Å |
| Cleft width | 19.23 Å |
| Cleft depth | 4.42 Å |
Aromatic clamp: PHE111, PHE215, PHE253, TRP139, TRP177, TYR227, TYR91
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKSKWIRAGATVLLMAGLLGTGYIESHKERALNTIDASAIATTLSAELGSENEEVPAQLLMCSTSTSQIETFRYWLYTPKNPVENMPLIVYLHGSSGKGDDLNILMNEDGFPQYLKNGQLGDIPAYILIPQLPAEKRGWASVSQSVYQLISETVSTCQIDSDNISLTGHSMGGTGTWNLAAQYPQMFARIAPLSGSARGQAAKLEALKEIPVRAFVGSDDTVILPEYSESAVSELNALGGNAQITIFEDADHFAVPSQTYLDPSISLVNWLIGNDAEKENDNETVL