PANTS-e858ce93d353
Human gut 264 aa · assembly ERZ24772404_FASTA_predicted_cds · contig ERZ24772404.12-NODE-12-length-280560-cov-57.762218_170
Retrieval
| E-value | 7.80e-11 |
| Bitscore | 29.2 |
| Identity to nearest | 0.308 |
| Nearest characterised | EC:A0A7K0C0L9 |
Structure
| Method | esmfold |
| Mean pLDDT | 88.7 |
| RMSD to IsPETase | 11.78 Å |
| Aligned fraction | 0.219 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S162/D211/H243 |
| Ser–His | 2.94 Å |
| His–Asp | 3.0 Å |
| Cleft width | 21.56 Å |
| Cleft depth | 3.48 Å |
Aromatic clamp: PHE125, PHE169, PHE215, PHE238, PHE250, PHE62, TRP108, TRP246, TYR206, TYR99
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MNRCILVTGVFLFLLSAGLFASDIDKYYAKKEYISPRRDTLRYRVLEPERIEKNKKYPLVLFLHGAGERGSDNEAQLVHGANMFLNPVIRDQHPTFVIYPQCPSECSWSNSSKPNSEGKSGGERFPENPEITIPMEAVKAVLDMYMNNDNVDVNRIYVMGLSMGGMGTFDLLCRFPDLFAAAIPICGGINPERLEKASPTTAITIYHGDKDDAVFVENSRAAYRALKKIGKTPRYIEFPGCGHNSWDPAFNQPDFLEWLFRQSK