PANTS-eed0edd3ca26
Human gut 268 aa · assembly ERZ4560321_FASTA_predicted_cds · contig ERZ4560321.1707-Hadza-MoBio-hadza-E-H-G-21-1740--NODE-1707-length-39562-cov-19.346309_7
Retrieval
| E-value | 6.60e-09 |
| Bitscore | 22.9 |
| Identity to nearest | 0.329 |
| Nearest characterised | EC:A0A239AX86 |
Structure
| Method | esmfold |
| Mean pLDDT | 88.8 |
| RMSD to IsPETase | 11.95 Å |
| Aligned fraction | 0.200 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S124/D172/H206 |
| Ser–His | 3.03 Å |
| His–Asp | 2.89 Å |
| Cleft width | 20.37 Å |
| Cleft depth | 4.34 Å |
Aromatic clamp: PHE133, PHE212, PHE213, PHE254, PHE52, TRP95, TYR128, TYR69
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MLTLILSASLQTKAQYDFIRPVKDAIPGGYNFWVYTPTEYYYTLNETPVIIFLHGQSLCGRDLNRVRRYGPLDAIVKGRQVDALVVVPQNPGGAWNPKKINDVLEWTKQNYACDSTRVYVIGMSLGGYGTLDFACTYPDKVAAALAMCGGCSKKDRTPLGKLPLWIIHGTADRAVSISQSKSVVNDLEKSGNDSRLRYTWLQGANHGAPARFFYMRKTYNWLFSHSLLDPDRPVNKEITLDMSDLPKAYRDMDFGKADPETVYETTIK