PANTS-fb53ed63ed40
Human gut 271 aa · assembly ERZ4560895_FASTA_predicted_cds · contig ERZ4560895.377-Hadza-MoBio-hadza-A-D-J-9-1548--NODE-377-length-54211-cov-10.052462_30
Retrieval
| E-value | 5.70e-09 |
| Bitscore | 23.1 |
| Identity to nearest | 0.273 |
| Nearest characterised | EC:A0A7W9IBT4 |
Structure
| Method | esmfold |
| Mean pLDDT | 91.1 |
| RMSD to IsPETase | 14.70 Å |
| Aligned fraction | 0.192 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S133/D181/H215 |
| Ser–His | 3.0 Å |
| His–Asp | 2.96 Å |
| Cleft width | 18.37 Å |
| Cleft depth | 3.57 Å |
Aromatic clamp: PHE142, PHE222, PHE264, PHE61, TRP104, TYR137, TYR268, TYR78
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKLKTIFLALLLLTTLAVHAATDGQGKMEAMRGKVPGSYNFWIFTPEEYEPEGRGVPLVIFLHGASLCGNNLEKVRRYGVLHAIQKGKIVPAVVLAPQNGGGAWNPKKINDLLEWTEAHYAIDTTRVYVLGMSLGGYGTMDFVAAYPDKVAAAMALCGGCSVKEPAGLGQVPLWIMHGTADRAVPIAQSKRVVDYLQQSGNDQLLRYDWIKGGNHGTPARLFYLQKTYDWLFSHSLHDSPRTVDRTFDIDMDDIRQTYDELRWFRGMYDND