PANTS-fe0c48eb7ac7
Human gut 263 aa · assembly ERZ24772406_FASTA_predicted_cds · contig ERZ24772406.31838-NODE-31840-length-1321-cov-3.618483_1
Retrieval
| E-value | 2.70e-10 |
| Bitscore | 27.5 |
| Identity to nearest | 0.267 |
| Nearest characterised | EC:A0ABV5TJR7 |
Structure
| Method | esmfold |
| Mean pLDDT | 89.8 |
| RMSD to IsPETase | 15.10 Å |
| Aligned fraction | 0.264 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S161/D210/H242 |
| Ser–His | 3.03 Å |
| His–Asp | 3.05 Å |
| Cleft width | 20.3 Å |
| Cleft depth | 3.61 Å |
Aromatic clamp: PHE168, PHE217, PHE237, PHE249, PHE62, TRP108, TRP245, TYR111, TYR124, TYR205
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MKTLRSIFFLSLCLLLSVAGYAGDKASFLKKQFTARDGYQLNYRVLYPRDYNPAQKYPVILFLHGAGERGSDNEAQLVHGGDMFASFENQTKYPAIIIAPQCPAEKTWSEYKGLNAGKEGKRFYPLNAPATQSMAAVKELLDSYIAEGKADTKRIYVTGLSMGGMGTFDIVMRYPNLFAAATPICGGANLQRLANFKGKTAFSIYHGGSDSVVDVQFSRDANEALKKAGADVRYKEFPGVDHNSWDNAFAEPDYLAWMFQHSL