PANTS-ffc51cae4d1c
Human gut 198 aa · assembly ERZ4560321_FASTA_predicted_cds · contig ERZ4560321.12015-Hadza-MoBio-hadza-E-H-G-21-1740--NODE-12015-length-9368-cov-5.654074_2
Retrieval
| E-value | 1.10e-07 |
| Bitscore | 18.9 |
| Identity to nearest | 0.293 |
| Nearest characterised | EC:A0ABT4UC71 |
Structure
| Method | esmfold |
| Mean pLDDT | 67.2 |
| RMSD to IsPETase | 12.34 Å |
| Aligned fraction | 0.185 |
Aligned fraction is a length-normalised gemmi superposition statistic, not a true TM-score.
Active site
| Triad | S99/D146/H178 |
| Ser–His | 2.82 Å |
| His–Asp | 3.03 Å |
| Cleft width | 22.27 Å |
| Cleft depth | 4.07 Å |
Aromatic clamp: PHE141, PHE18, PHE74, TRP106, TRP181, TRP44, TYR101, TYR103, TYR183, TYR185
Structure, superposed on IsPETase
Catalytic triad drawn as ball-and-stick from the measured residues.
Sequence
MEKERGIIPKTVWLPDVFGNSYGMPQILAKSGIKYFVTHKPCVWNDTNQIPHHTFWWQGPDGSRVFAALSASHFVGTCELDHIMLNWGRYTDKAKIGESMYSYGTWHTAMARPDLFAAIAPICGGGMAWNAHVLKMPAWVFHGAADETVSVNQSDEMVNAMRANGTDVKYTRMDGVGHGVWDYAYTDEMVKWLLSHQI